Obviously, inadequate knockdown of gene expression is one way.
Gene transfer trials for heart disease have thus far been disappointing perhaps because of inadequate levels of gene expression in the heart.
Decreased binding is thought to result in inadequate downregulation of TNF gene expression and therefore increased TNF production.
Most of the available evidence concerning widespread variation in gene expression is inadequate, because it involves circular reasoning.
None of the 15 known or supposed markers for CTC detection was considered for further investigations either due to detectable expression levels (ERBB2, ESR1, SERPINE1, SERPINE2 and FN1) in healthy controls or due to inadequate gene expression in the tumor cell lines.
Those "ubiquitous" promoters, however, are inadequate for meiotic purposes, because they drive gene expression in meiosis at an insufficient level [ 62].
While this represents a better segregation of asthmatics and non-asthmatics than seen with the gene expression, the group sizes are inadequate for meaningful interpretation.
Gene expression was normalized against expression of the GhEF1α gene.
We argue that these properties make simple least-square distance estimates among individual gene expression time-series uninformative and biased, being inadequate for process description [ 26, 93].
Nevertheless, our work demonstrates that chemical structure is indeed related to gene expression profiles, but using chemical structure alone is inadequate to model expression changes.
Inadequate correction for the search space and reliance on assumptions of normality in gene expression can lead to false inferences of epistasis where none exists.
