These include inadequate warm-up, fatigue, previous injury, knee muscle weakness or strength imbalance, increasing age, poor movement discrimination, poor flexibility, increased lumbar lordosis and poor running technique [ 6- 8].
There have been many concerns about ICS, its poor flexibility and scalability, and "lack of use, misuse, underuse, [and] partial use" as a root cause of inadequate and insufficient response to recent emergencies (Jensen and Waugh Jr 2014, p. 12).
Specific factors to note should include excessively snug shoe fit or lacing, arch support that does not adequately deform under loads that occur in landing or jumping, and inadequate sole flexibility in the forefoot region.
The analysis of the SOL program results from the CSAR competition indicates that such a failure in ligand positioning and as a consequence failure in inhibition activity prediction may be the result of the inadequate protein flexibility model (potentials grid with broadening) and inaccurate solvent model.
Others cite structural or institutional barriers, like bias, discrimination or inadequate work-family flexibility.
A key hurdle to meet the needs of micro/nano manipulation in some complex cases is the inadequate workspace and flexibility of the operation ends.
However, as with all methodologies, these models have many limitations, inherent but inadequate assumptions, and lack the flexibility required to represent appropriately clinical reality [ 27].
Inadequate hospital bed capacity and flexibility, or lack of an available bed when it is needed, result in the delay of transfer of patients from ED to an appropriate in-hospital bed, particularly to medical and surgical wards as well as ICUs [ 5- 7].
Conventional risk modelling approaches are considered to be inadequate due to the lack of flexibility and an inappropriate structure for addressing the system's risks.
