Sentence examples for inadequate differentiation from inspiring English sources

During chondrogenesis from mesenchymal stem cells (MSCs), inadequate differentiation and hypertrophic differentiation are two important limitations.

Inadequate differentiation of these layers leads to detrimental changes in placental architecture, which affect the supply of nutrients or oxygen to the fetus.

In this regard, the inadequate differentiation of nestin cells to a neuronal phenotype may in part contribute to the impaired neurogenic response reported during wound healing of injured diabetic tissue.

This may result in T cell activation and diminished B-cell immunological response as the consequence of inadequate differentiations into plasma cells.

While directed differentiation and transcription factor-mediated conversion strategies have generated progenitor cells with multilineage potential, to date, therapy-grade engineered HSCs remain elusive due to insufficient long-term self-renewal and inadequate differentiated progeny functionality.

Weak points of the system include inadequate spatial differentiation of socio-economic characteristics, scarce database for quantifying perennials and mixed cropping systems, and insufficient consideration of long-term effects of production technologies on resource quality.

Upregulation of the melusin gene may alter a process that is tightly controlled in muscle development, leading to inadequate muscle differentiation and maturation.

In contrast, the overexpression of PRB leads to premature arrest of ductal growth and inadequate lobuloalveolar differentiation [ 16].

These findings indicate that the KL-6 concentration of pancreatic juice is clinically useful when PJC specimens are inadequate, making differentiation between malignant and benign conditions difficult.

Human trophoblast progenitor cells differentiate via two distinct pathways, to become the highly invasive extravillous cytotrophoblast (CTB) cells (EVT) or fuse to form syncytiotrophoblast. Inadequate trophoblast differentiation results in poor placenta perfusion, or even complications such as pre-eclampsia (PE).

However, this concept has been limited by inadequate and inconsistent differentiation of BMSCs into cardiomyocytes along with poor survival and integration of neo-cardiomyocytes after implantation into ischemic myocardium.