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In some cases, excessive resorption of the septum primum (drawn in red) or inadequate development of the septum secundum (drawn in blue) or a combination of both occurs.
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FADD-deficient mice are embryonically lethal because of inadequate development of, for example, the vascular system, and FADD-deficient T cells show reduced proliferation suggesting an important role of FADD in developmental signaling.
The lack of protective effect of FI-RSV vaccine and its correlation to a more severe infection were probably due to several factors, including inadequate development of incomplete affinity maturation of the antibodies, poorly neutralizing antibodies against RSV encoded epitopes, and lack of an anti-RSV cytotoxic T lymphocyte response [ 73].
On top of that we are eating less fresh fruit and vegetables and some scientists link a lack during childhood to the inadequate development of a normal immune system.
Little attention has been paid to the effect of inadequate development of interventions before proceeding to a full clinical trial.
Frequent rate of RSV reinfections throughout the childhood implicates inadequate development of Th1 and Th2 responses which is evident from simultaneous IFN- γ and IL-4/IL-5 production [ 2, 3].
A link between distress or dissatisfaction in the veterinary workplace and inadequate development of graduate attributes has been suggested [ 6].
Factors affecting nurse-doctor relationships suggested to the respondents included 'cultural demands' of respect from the younger generation, informal relationships, inadequate development of interpersonal skills, personal characteristics and refusal to take advice.
Sir Nicholas Hytner, artistic director of the National theatre, told the report's authors: "The consequences of inadequate public investment will be fewer risks, inadequate development of new work, a substantially less interesting theatrical environment and a less successful one".
"There was inadequate development of a workforce strategy or consideration given to recruitment, support and development of staff competent to deliver the care required," the report states.
Patients in the NICU have intrinsic risk factors for infections due to immunological "deficiencies" or inadequate development of mechanical barriers such as skin and gastrointestinal tract mucosa.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com