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It is not known whether weight loss in DS patients is due to increased energy consumption, inadequate absorption, or both.
Zinc deficiency is especially common in lower income countries due to the low dietary intake of zinc-rich foods and inadequate absorption.
Undernutrition is defined as insufficient intake of nutrients, but can also be the result of inadequate absorption or metabolism of nutrients.
However, the symptoms of vitamin B12 deficiency caused by poor diet, digestive problems, and/or inadequate absorption in elderly people can be nonspecific, rendering a diagnosis more difficult.
Abnormal ventricular accumulation of cerebrospinal fluid (CSF), due to obstruction of flow, inadequate absorption, and/or excessive production, results in elevated intracranial pressure (ICP) and ventricular dilation.
Despite appropriate antimycobacterial treatment, the relatively low doses of isoniazid (5 mg/kg), poor adherence, or inadequate absorption of drugs because of HIV-related gastrointestinal disease may have resulted in subtherapeutic in vivo drug concentrations and thus in selection of a drug-resistant M. bovis BCG strain.
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In humans, clopidogrel resistance can occur in the case of inadequate compliance, poor absorption, non-optimal dosages, smoking, gene polymorphisms or drug interactions [ 46].
The mechanisms for growth deficiency in CHD are multifactorial 7– 13 and include associated chromosomal anomalies/genetic syndromes, inadequate nutritional intake due to feeding difficulties, and poor absorption of nutrients from the digestive tract in chronic congestive heart failure (CHF).
It has been suggested that inadequate nutritional absorption of essential fatty acids may play a role in the altered bone metabolism.
Most frequently the use of bioactive molecules for the supplementation of food and beverages is hampered by stability limitations or inadequate intestinal absorption.
Appropriately, cushioned footwear redistributes and reduces plantar pressure [13, 15], while inadequate shock absorption will transmit large forces through the body, potentially resulting in injury [13, 15, 45, 46, 55, 56].
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