Sentence examples for inactive variants from inspiring English sources

Therefore, the number of inactive variants was the same for all four organic solvents.

Column "×" shows that the number of inactive variants resulted from amino acid substitutions.

Inactive variants were defined as variants which showed no detectable activity in buffer.

The number of inactive variants was the same for all organic solvents.

At the approximate junction of these two sections are a conserved serine and glutamate that are hydrogen bonded and associated with H2O2 in inactive variants.

These libraries, however, contain mostly inactive variants, and the very low frequency of improved variants can only be isolated by high-throughput screening.

A structure based suppression strategy permits the inactive variant Flp(W330A) to be rescued by a second site mutation A339M.

Here we aimed to investigate whether an enzymatically inactive variant caspase-1 (p.C284A) leads to the alteration of speck formation and pyroptosis, a caspase-1 dependent proinflammatory cell death.

Applying live cell imaging, we for the first time show that pyroptosomes of enzymatically inactive variant caspase-1 spread during cell division.

In the inactive variant, a third class of N-terminal conformation is observed, which arises from a conformational change in the position of F17.

Substitution of Trp164 by His also resulted in an inactive variant, indicating that an indole side-chain is required for activity.