Exact(3)
In either case, the inactive sate is stabilized by interactions involving TM3 with both TM5 through P5.50 and TM2 through its bulge at position 2.56 or 2.57.
GDIs associate with GDP-bound GTPases and prevent these from membrane-association, in effect sequestering them in an inactive sate.
The G protein active state of the receptor likely does not have this water binding site as the helical turn after Pro has a little unwinding such that the distance between the residues in the inactive sate increases, making it difficult to form several hydrogen bonds with a water molecule at the same time to keep the water molecule around these residues.
Similar(55)
The fully extended chains, on the other hand, masked the peptides completely and the cells started to detach from the surfaces at inactive "off" sate below the LCST.
Is the consumer still sated?
She never understood inactive.
Johnson was inactive.
But not an easy desire to sate.
Beef sate was another surprise.
His blog is inactive.
Inactive children tend to grow up to be inactive adults.
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