Sentence examples for inactive orientation from inspiring English sources

This lowered α-KG turnover of ALKBH8 has been attributed to the catalytically inactive orientation of α-KG and Arg334 in the active site, which requires a conformational change upon tRNA binding to be catalytically active.

If the interactions between the protein and support are not carefully designed, there is a tendency to produce reactors possessing randomly oriented proteins with some orientations providing inactive forms.

To maintain genomic stability, separase must be kept inactive before chromosome bi-orientation in metaphase.

Thus, mono-orientation with inactive Mps1 is not caused by a failure to establish functional kinetochores after DNA replication [22].

Another explanation for sister centromere mono-orientation with inactive Mps1 is that only a single kinetochore from each pair of sister centromeres is functional.

Failure in bi-orientation with inactive Mps1 is not due to a lack of kinetochore-spindle pole connections by microtubules, but due to a defect in properly orienting the connections.

For the first time, the spin axis orientation of an inactive box-wing geosynchronous satellite has been estimated from ground-based optical photometric observations of Echostar-2's specular reflections.

The bi-orientation defect with inactive Mps1 was therefore not due to an impaired spindle-assembly checkpoint.

Predicted proteins containing this curious combination of domains, in the same orientation and including the inactive kinase, can also be found in plants but not apicomplexans or ciliates.

As indicated in Table 1, in the inverted orientation, M'E (#655) was inactive.

Interestingly also the isolated SH3 SH2 domains of Fyn maintain the relative orientation observed in the closed inactive kinase conformation of Src [ 17].