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Inactive data points used for this test are based on presumed inactivity, producing an approximated indication of the true extrapolative ability of the models.
To balance the class sizes, a sphere exclusion algorithm was used to extract putative inactive data.
Including inactive data for models improves the recall and precision AUC and BEDROC performance.
Fig. 7 Precision-recall curve for the models including inactive data, and actives-only models.
However, the true inactive data are hardly available in most public databases, thus significantly restricted their usages in target fishing.
Including inactive data for models improves the recall and precision as shown by the AUC values for both plots, showing value for including inactive data when compared to models built exclusively on ChEMBL data Fig. 8 Boxplot of precision-recall curve AUC and BEDROC values for the models including inactive data, and actives-only models.
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Such algorithms would therefore require large scale undersampling of inactives data points to obtain acceptable performance, thus sacrificing the coverage of inactivity space.
Pattern recognition (PR) is a multivariate technique that is well suited for the qualitative, active-inactive, data that is often supplied by biological assays.
SCTP does not use any path marked as "inactive" for data transmission.
If inactive users' data is not deleted, it could potentially be re-used for other purposes long after the user left the service," it writes.
A canine study [30] investigating both bone and muscle perfusion reported perfusion levels comparable to inactive pig data.
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