The others were, respectively, capsules of hyaluronic acid loaded with siRNA alone, similar capsules loaded with doxorubicin and an inactive control RNA, and the full combination of hyaluronic acid, siRNA and doxorubicin.
The inactive control ribozymes showed no cleavage.
The oligonucleotides were used as AS1411: 5′-d (GGTGGTGGTGGTTGTGGTGGTGGTGG -3′, and an inactive control oliGGTGGTGGTGGTTGTGGTGGTGGTGG -3′CTCCTTCTCCTCCTCCTCC)-3′.
MAEC were transduced with small hairpin (sh) RNA to knock down PIN1 (KD) or an inactive Control shRNA.
Experiment 3 replicated the results of Experiment 1 using an inactive control group, showing that playing Alien Game for 2 h resulted in significant improvements in shifting skills (d = 0.78).
CL1-5 cells were first incubated with UV-treated inactive control helper phage (insertless phage).
The same amount of tetanus toxin was boiled for 5 minutes prior and used as inactive control.
Two different JunB siRNAs inhibited JunB protein expression by >65% as compared with an inactive control siRNA in INS-1E cells (Fig. 2A, quantification in Fig. S2).
To determine whether JNK2 activation can affect the β-catenin-driven gene transription, MKK7-JNK2 was co-transfected with β-catenin into HEK293T cells along with TCF-4 reporter plasmid TOPFLASH or the inactive control FOPFLASH.
It may be that one hundred percent certainty that one is receiving the "treatment of interest" (in this case open-label placebo) is more placebogenic than a fifty percent probability of receiving an inactive control.
Comparison: Inactive control (no offer of screening or standard care).
