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Prodrugs are biologically inactive agents that upon biotransformation in vivo result in active drug molecules.
This contrasts with current street supplies of ecstasy and speed, which are often very low quality after being cut with inactive agents and may even contain some other, more dangerous, drugs such as methylamphetamine.
In the introduction to "America's Black Past," an anthology published in 1970, the historian Eric Foner wrote that, among this country's "myths and misconceptions, one of the most pervasive and pernicious . . . is the picture of blacks as inactive agents in history".
For example, a randomized trial of just 100 patients could lead to the termination of development of 90% of inactive agents whereas at least 80% of agents with a meaningful and realistic increase in progression-free survival would be identified for confirmatory study.
Completely inactive agents are not included in the ni counts.
Although this may be due to inactive agents or a failure to rigorously validate drug targets, the authors have previously demonstrated that catheter positioning plays a major role in drug distribution using this technique.
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The CSR incorporates EPD, based on estimates of TTP, in the stage I decision-making process to provide an early signal of drug inactivity and allow for early termination of an inactive agent.
We would call him an inactive agent". Pacific Standard has sold insurance to a handful of Carson city employees since 1969, Cobo said.
For this to be translated into the clinic the active agent would have to be purified to separate it from the inactive agent.
In all instances, inappropriate therapy occurred not because of the use of an in vitro inactive agent but because of a delay in the initiation of antibiotics.
For their capacity to rapidly inactive infectious agents and to probably inhibit the emergence of drug resistance, AMPs have attracted considerable attention, especially for the treatment of antibiotic-resistant pathogens.
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