Sentence examples for inactivating effect from inspiring English sources
The direct virus inactivating effect of CAP, the multiple mechanisms involved in prevention of HIV-1 infection, the broad spectrum activity against several STD pathogens, the established safety record, low cost and availability in large scale suggest that CAP has advantages over other polymeric substances considered as topical (vaginal) microbicides for prevention of STDs, including AIDS.
In a recently published study, a moderate inactivating effect of HHP of 350 MPa about 10 minutes, which had been shown to eradicate cholesteatoma cell growth on explanted human ossicles without harming the ossicle itself [ 44], was shown for colonizing microbes (scheme of experimental setup in Figure 1) [ 23].
It is highly biocompatible and biodegradable and can encapsulate both hydrophilic and hydrophobic pharmaceutical agents and protect them from the inactivating effect of external condition.
In addition, the use of a more sensitive cell assay for Stx would be likely to detect the inactivating effect of the gas plasma on Stx at an earlier treatment time, because efficient degradation of Stx1 and Stx2 within 5 or 15 min of treatment was shown by all biochemical assays, including immunochromatography, ELISA, and Western blotting.
Recent reports have described that SIRT1 shuttles to the cytoplasm upon oxidative stress rendering it incapable of exerting its inactivating effect on anti-apoptotic substrates within the nucleus and consequently sensitizing cells to oxidative-stress mediated apoptosis [8], [27].
The susceptibility to the inactivating effect of MMTS of these two chimeras is shown in Figure 2 Panel c. Remarkably, the chimeras showed an overall intermediate response between the susceptible WT TcTIM and the resistant WT TbTIM.
However, treatment with NY 3170 in combination with cis-DDP induced increased cell inactivating effects equal to a doubling of either the concentration of cis-DDP or treatment time.
The water extract of P. guajava leaves was found to be effective in inactivating the mutagenic effects of agents such as 4-nitro-o-phenylenediamine, sodium azide and 2-aminofluorene on S. typhimurium in Ames assay [ 57].
ROS also react directly with NO to form peroxynitrite species, thereby inactivating the vasodilatory effect of NO, which is integral to vascular homoeostasis and endothelial function.
Glutathione S-transferases (GSTs) play an important role in detoxification of various toxic compounds like carcinogens in cigarette smoke and tobacco by conjugating to toxic compounds and inactivating their hazardous effect.
However, low concentrations of the three essential oils (0.2 μl/ml) in combination with a mild heat treatment (54 °C/10 min) showed synergistic lethal effects, inactivating more than 5 log cycles of bacterial cells, and demonstrating their potential in the design of successful combined treatments for food preservation.
