Sentence examples for inactivated status from inspiring English sources

It can sequester cyclin D1 in the cytoplasm in an inactivated status.

Subsequent studies have shown that this hypomethylation is not primarily associated with gene-specific methylation, as numerous tumor-suppressor genes in cancers were found in hypermethylated (an often inactivated) status [ 43, 44].

Computational studies comparing the genomic neighborhoods of genes with different inactivation status have supported that inactivated and escape genes have different genomic environments with respect to the content of repetitive sequences (Bailey et al. 2000; Carrel et al. 2006; Wang et al. 2006; Nguyen et al. 2011).

Such genes therefore have a differential penetration on the basis of their inactivation status: since only one copy of the inactivated genes is functional in females and there is only one copy of X linked genes in males, any mutation in the inactivable genes would have a greater effect on the phenotype.

Methylation at L1P and L1M did not correlate with the inactivation status of the host DNA, while the majority of L1Hs that were possible to be studied lie in inactivated regions.

Otherwise, we reported [16] that in breast cancer cells, in spite of the presence of two or more X chromosomes, none of them is functionally inactivated, irrespective of BRCA1 status, and all the X chromosomes are copies of native active X (Xa).

Virus inactivation was confirmed by incubation of MDCK cells with the heat-inactivated stocks and the infection status of the cells was monitored by virus-specific immunofluorescence staining (no infected cells were found).

The cells successfully reverted to the normal status were used to identify the inactivated genes.

Separate stratified VE analyses by vaccine type (trivalent inactivated [TIV] or live attenuated [LAIV]), age groups and hospitalization status were also performed.

In 1997 approximately 20 Danish beef herds, with confirmed BRSV positive status, received a temporary permission to use an inactivated vaccine against BRSV in calves.

These findings indicate that maintenance of inactivated p53 wt in melanomas and gliomas is directly associated with p14ARF/HDM2 status and that this axis may serve as a therapeutic target [ 11].