Sentence examples for inaccurate replication from inspiring English sources

Differences in wetting behavior between natural leaves and artificial leaves originate from an inaccurate replication of the chemistry and structures of the three-dimensional wax projections on the leaf surface.

The case v = 0.01 is intended to model the situation in early cells with very inaccurate replication.

We began with individuals with v = 0.01 and h = 0.6, representing early cells with inaccurate replication and frequent HGT. Figure 3 shows mean values v ¯ and h ¯ as a function of time.

In the bottom-middle panel (step 8 × 10), the 32-nt RNAs increase, probably representing the chromosome, along with a few variants caused by inaccurate replication (associated with P FP and P FLR in the model).

To achieve an inaccurate genome replication, genetic perturbations on genome replication machinery are generated by constructing a mutant library of a proofreading element (PE) gene, designated as PEM-lib.

Therefore, this sequence variation suggests that MITE transposition may not be a simple "insertion" or "excision" process and possibly involves an inaccurate DNA replication mechanism, such as break-induced replication (BIR).

Inaccurate genome replication will be triggered in cells containing PEs with decreased proofreading activities, thus continuously generating offspring cells containing different genomic mutations.

Offspring cells with mutated genomes that survived the increased selective pressures will be selected during the continuous enrichment processes, and the genomic feature of evolved cells with improved phenotypes can be stably maintained once the elements triggering the inaccurate genome replication are removed from the individually isolated cells.

DNA repair in the coding regions of the mitochondria is biased toward gene conversion, reducing the mutation rates within genes, whereas the more inaccurate break-induced replication (BIR) is common in the noncoding regions, leading to the expansions and rearrangements observed outside of genes [ 12– 15].

Mutation rates determination based on this indicator showed that E. coli cells carrying pQ-dnaQ-KR5-2 exhibited a 317-fold increased mutation rate than that of the wildtype control, confirming that introducing genetic perturbation into genome replication machinery indeed triggered inaccurate genome replication.

BIR is a highly inaccurate cellular process that mimics normal DNA replication in its processivity, rate, and capacity to duplicate hundreds of kilobases, but is initiated at double-strand breaks (DSBs) rather than at replication origins [ 22].