Sentence examples for inaccessible target from inspiring English sources
It is an extremely hard and almost inaccessible target, but this is our goal.
Their types and installation positions were defined taking into consideration the detailed information coming from a dedicated thermal electric model that allowed to investigate the most critical and inaccessible target hot-spots.
The brainchild of a Pennsylvania dentist, the idea involved strapping small incendiary bombs to bats and releasing them to spread fires in inaccessible target zones.
These cells are readily accessible in humans compared to the relatively inaccessible target tissues of PPARγ ligands, namely adipose tissue and liver [ 5].
Measures of DNA methylation hold substantial promise as a biomarker for toxic environmental exposures, but because such marks are specific to cell type, much work is still needed to determine what role, if any, WBC DNA methylation may have for diseases that occur in inaccessible target tissues, such as the brain.
Furthermore, whereas Overhoff et al. [ 26] found an improvement in siRNA efficacy based on target accessibility, they also noted that not all siRNAs against inaccessible targets are ineffective.
Recombinant polyproteins that use similar mechanisms are emerging as powerful tools for producing hitherto inaccessible protein targets such as the influenza polymerase, for high-resolution structure determination by X-ray crystallography.
However, it has been shown that the infecting retroviral genome is apparently shielded by RNA-binding proteins rendering it inaccessible to targeting by RNAi factors [ 60].
Antichemotherapy drugs are inaccessible to the targets as the glycosylated MUC1 inhibits from reaching its targets.
Moreover, the formation of enzyme substrate complexes, a critical intermediate step to facilitate the enzymatic reaction, would be affected or even suppressed if the peptide substrate is deeply embedded inside the assembled nanostructures and inaccessible to its targeted MMPs.
Ariel Zylbersztejn, the managing director of Mexico's Cinepop, by contrast, boasts that his entertainment-based platform allows business and government to target otherwise inaccessible markets.
