Sentence examples for inability to traverse from inspiring English sources

Two pharmacological barriers, however, remain a major obstacle to the development of peptide therapeutics: susceptibility to proteolytic degradation in vivo and inability to traverse the cell membrane.

Unfortunately, PTAX has no beneficial clinical effect in halting the growth of brain tumors or extending the life of patients with brain tumors largely due to its inability to traverse the BBB [82], [83].

However, because of degradation, inactivation and inability to traverse an intact BBB, catalase has major hurdles impeding therapeutic use.

The clinical use of agitated saline is, however, very limited due to the very short life (a few seconds) of air microbubbles and their inability to traverse the pulmonary circulation.

Whereas the simplest approach, conceptually, would be to use antisense or RNA interference methods to knock down the pathogenic RNA itself, such approaches remain difficult due to the general inability of such agents to traverse the blood brain barrier.

However, the inability of macromolecules, like enzymes, to traverse the blood brain barrier (BBB) in sufficient amounts so to alter the CNS lysosomal storage has led to the search for alternative methods of treatment.

Our study demonstrates that inactivation of Rnase10 results in a reproductive failure consequent to an inability of the KO spermatozoa to traverse the UTJ and gain the site of fertilization, while their fertilizing ability per se is enhanced.

New Hampshire is easy to traverse.

Who wants to traverse that steep Appellation Trail?

Then he had managed to traverse several Alpine passes.

need a shuttle bus to traverse its 194-acre campus.