We postulated that inability to demonstrate response in non-BRCA carriers in which BRCA is inactivated by other mechanisms or with deficiency in homologous recombination for DNA repair is due to lack of molecular markers that define a responding subpopulation.
However, the inability to demonstrate GFP expression in vivo meant that we were unable to address this categorically and a small possibility must remain that the transplanted urothelium provided a "feeder" effect that promoted ingrowth of native urothelium.
But many schemes experience poor rates of attendance, a factor that may contribute to their inability to demonstrate effectiveness [ 7, 8].
Pitfalls that can result in false-negative diagnoses include retained fluid, which can obscure lesions, incomplete distention of some colonic segments, and inability to demonstrate flat lesions.
Because of their inability to let this issue go, and their willingness to continue to demonstrate that immigration will be the defining issue of 2016, Republicans have resorted -- once again -- to stall the inevitable.
4 Observational studies appear to demonstrate that mothers' employment could be detrimental to child nutrition 5 8 due to their inability to devote adequate time for feeding and care.
A major challenge in human GWA studies is the inability to directly demonstrate that a candidate SNP causes the phenotypic variation.
These studies and the inability to reproducibly demonstrate that the paradoxical growth effect occurs in vivo have raised the question whether this phenomenon is an artifact of in vitro growth (Jacobsen et al., 2007; Wiederhold, 2009).
Interval's inability to publicly demonstrate technology breakthroughs has been an issue that has plagued the research center in recent years.
