This subset of probes has a disproportionate effect on the mean because of the inability of the technology to detect differences between poorly hybridizing probes and very poorly hybridizing probes.
Thus, a question posed by these studies is whether the relative scarcity of cancer gene 'mountains' is a genuine feature of the cancer muta-ome or whether it merely reflects the inability of the technology to detect further high-frequency mutations.
This differential reflects the inability of current microarray technology to significantly resolve smaller differences in levels of gene expression.
Policy-relevant research is needed to develop health interventions and measure their impact, address social determinants of health, understand failing health systems, and make sense of the inability of many health technologies to deliver their expected impacts in Africa.
This could be due to an inability of current LC-MS/MS technology to confidently detect low abundance proteins, most of which [except for matrix metalloproteinases (MMPs)] are strongly expressed only at stages of regeneration beyond accumulation blastema (see [ 10] for review).
The global nature of technology and the inability of politicians in one jurisdiction to control access to software or algorithms developed elsewhere makes political attempts to outlaw encryption as futile as they are historically repetitious.
Harrison speculates that a knowledge of extraterrestrial technologies could increase the gap between scientific and cultural progress, leading to societal shock and an inability to compensate for negative effects of technology.
The legislation may result in severely impaired ongoing investigations and lengthen the time it takes to catch criminals -- a key example of the inability to effectively balance the benefits of technology and privacy concerns.
It was the inability of voters to use that technology properly and the lack of trained poll workers to instruct them.
Shweta Singh, of Lombard Street Research, said Italy's weakness since the turn of the millennium was the result of three factors: a slow takeup of new information technology; the inability of the government to devalue the currency to restore competitiveness; and the challenge posed by China in many of the markets where Italy has traditionally been strong.
