Sentence examples for in which targeted from inspiring English sources

To date, C. acetobutylicum and C. thermocellum are the only clostridial strains in which targeted gene deletion via homologous recombination have been established [36], [37].

Briefly, shRNA and GFP were stably transduced into cells via retroviral vectors; therefore, cells in which targeted genes were knocked down also express GFP.

Well-developed informatics tools are able to analyze miRNA sequence datasets, predict the mRNAs regulated by any detected miRNA, and determine the pathways in which targeted mRNAs function.

Few efforts have been made to collect and use full-length cDNA sequences in filamentous fungi, in which targeted gene deletion mutants could readily be obtained by homologous recombination due to the haploid nuclear status.

These results established a promising blueprint for gene therapy of sickle cell disease and β-thalassemia in which targeted gene activation in a patient's own cells could compensate for the genetic disorder.

The number of samples in which targeted proteins (peptides) were detected in one, two or three technical runs was counted; some examples are shown in Table 1.

The future direction of cancer targeting is a combinatorial approach, in which targeting therapies are designed to use multiple-targeting strategies.

Kam et al. reported an approach similar to that of Chakravarty et al., in which targeting effects were achieved by using PL-PEG-FA functionalized SWCNTs [80].

However, false positive rates are high, as interactions may be predicted in physiological settings in which targeting does not naturally occur.

Therefore, the following sections deal in a speculative way with the various settings in which targeting the PARs may prove of therapeutic value.

The FoxM1-PTTG1 pathwey we have identified will help to define the proper therapeutic window in which targeting FoxM1 or PTTG1 can achieve clinical benefits.