Sentence examples for in which par from inspiring English sources

Given the complexity of the intracellular signalling networks, the ability of PARs to generate a 'biased signal' adds yet another layer of flexibility to the ways in which PAR activation can regulate cell and tissue behaviour.

Relative electron transport rate (rETR) was calculated as rETR = yield × PAR ×   A  × 0.5, in which PAR symbolizes responses to photosynthetic active radiation (A, absorbancy index = 0.85 in this study).

As another example, in endothelial cells two PAR protein complexes have been identified, a "conventional" PAR-3 aPKC PAR-6 PAR-3 aPKC PAR-6complexR complex in which Pand3 and PAR-6 are independently asecondted with VE-cadherin and which lacks aPAR (Iden et al. 2006).

The stadium is owned by a company in which Pars owner Gavin Masterton is the biggest shareholder.

describe another essential control mechanism in which Par-1, GSK-3, and an SCF ubiquitin ligase induce Oskar degradation to prevent ectopic or excess Oskar from disrupting patterning.

The examples are not meant to be comprehensive, but rather illustrative of several pathophysiological settings in which PAR-receptor kinase transactivation can play a role.

Together, these suggest that TGF- β induces EMT in multiple cell lines, a process in which Par-4 has a potential role.

Mouse epidermal stem cells contact the basement membrane via Integrins, can divide along the apical-basal axis of a polarized epithelium, and undergo an asymmetric division in which Par-3 is segregated into the apical daughter cell (Lechler and Fuchs, 2005).

The role of Slmb in oocyte polarity raises an intriguing parallel with C. elegans axis formation, in which PAR-2 excludes the anterior PAR complex from the posterior cortex to induce polarity, but its function can be substituted by overexpressing Lgl.

These mechanisms whereby PARs can 'crosstalk' via direct and indirect interactions with other GPCRs and with other signal-generating targets add substantial signalling complexity over and above the ways in which PARs can regulate cell function by transactivating receptor-kinases.

Initial visual acuity in eyes in which pars plana vitrectomy was performed was lower than in all the other treatment groups (0.86 LogMAR versus 0.7 LogMAR in the anti-VEGF group, 0.69 LogMAR in the triamcinolone group, 0.39 LogMAR in threshold grid, and 0.36 LogMAR in the grid subthreshold group).