Exact(3)
Among the 147 pathways, we selected 18 pathways, in which each pathway should have at least 5 identified proteins as well as more than 10% coverage of all the pathway-proteins in the database, to evaluate the pathway-bias between non-diabetic and diabetic serum.
The distinct neurochemical and receptor profiles of the striatonigral and striatopallidal MSN has enabled the generation of transgenic mice in which each pathway can selectively be activated or silenced (reviewed in [ 158, 159]).
We then assessed the significance of the compound sharing by generating 10,000 randomized pathway linkage networks in which each pathway had the same degree as in the observed network.
Similar(57)
The extent to which each pathway participates in the total deposition scheme is a function of reactor geometry, operating conditions, and the degree of precursor mixing as determined by the design of gas delivery systems.
In this approach, gene expression data are first aggregated at pathway level to transform the original data into a compact representation in which each row corresponds to a pathway instead of a gene.
The principal remaining sources of unwanted signals are coherence pathways in which each β pulse affects two spins at once.
This work will help us to understand and identify the functional relationships between gene families and the regulatory pathways in which each family is involved.
As signaling networks become better understood, it becomes more apparent that signal transduction does not take place in the context of independent linear pathways in which each protein is exclusively controlled by the preceding protein in the cascade.
The identity of the metabolites, the KEGG pathways in which each metabolite is involved, and the PCP-induced alteration in the overt level of each metabolite (as determined by SIEVE analysis) are shown in Tables 2 and 3 for the top and bottom cluster, respectively.
IPA was performed to discern molecular and cellular functions and canonical pathways on the basis of over-representation analysis, in which, for each pathway, the fraction of PDGFC-associated gene expression profiles involved in that pathway was compared to the fraction of human genes involved in that pathway.
To evaluate the contribution of each pathway to apoptosis, we used a simulation protocol in which only one pathway was activated while the other two pathways were inactivated.
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