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To confirm experimentally the prediction of the alternative splicing events in the bioinformatic analysis, eight transcripts in which alternatively spliced fragments were more than 100 bp were chosen randomly.
A recent comparative study in which alternatively spliced genes of a wide range of eukaryotes were compared has revealed that genes encoding proteins with particular activities, for instance DNA-, RNA- and calcium-binding, had elevated levels of AS [ 15].
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While MAPK signalling in melanocytes is typically driven through BRAF, BRAF activity is not required for MAPK activation in NRAS-mutant melanomas, which alternatively rely on CRAF signalling (Dumaz et al, 2006).
Borrelia burgdorferi (Bb) locomote by the beating of two opposing sets of endoflagella which alternatively drive them in opposite directions along their axes.
We define twintrons as such an arrangement in which the alternatively spliced U12-type and U2-type introns occupy the same genomic location and are processed by different spliceosomes.
With proactive behaviors being self-initiated, future-focused, and change-oriented (e.g., Grant et al. 2009), they comprise employees' discretionary behaviors in situations, in which they may alternatively proceed without immediate consequences such as when solving issues before they become an actual problem (Frese and Fay 2001).
Its rays bounced off the softly breaking waves, which had created a mini tide pool in which the Sandpipers alternatively danced and bathed.
This is the case for vertebrate viruses in which the avibirnavirus alternatively clusters with one of the two fish birnaviruses.
Evidence suggests that AD evolves through distinct patterns of WM disruption, in which retrogenesis or, alternatively, the Wallerian degeneration may prevail.
Exon-skipping events, in which exons are alternatively included or spliced out of the mature mRNA, affected mostly one or few exons, especially those involving putative AS shared between both samples (Supplementary Figure S3).
BMI category specific effect estimates for ΔPM10 were derived from four different models, in which BMI was alternatively centered at each of the mean values of the four BMI categories.
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