Sentence examples for in vitro screening systems from inspiring English sources
A further application of pulmonary cells grown in vitro from stem cells is the construction of in vitro screening systems for pharmaceutical or toxicological applications.
To optimize the suggested structure, over 130 derivatives were synthesized and their inhibitory activities on T-type calcium channel were assayed using in vitro screening system with α1G and α1H clones.
One of the main barriers that has inhibited drug development targeting metastasis has been a general unavailability of good models and, in particular, of an in vitro screening system capable of identifying candidate compounds.
Using an in vitro screening reporter system that allow to characterize hPXR activators and a first step of chemical modifications of an original agonist ligand (C2BA-4, 1- 2-chlorophenyl -N-[1- 1-phenylethyl -1H-benzimidazol-5-yl]methanesulfonamide), we identified compounds with a N-1- 2-chlorophenyl -N-[1- 1-phenylethyl -1H-benzimidazol-5-yl]methanesulfonamideists.
Different in vitro screening techniques were carried out.
Multiple approaches will be used, including field and in vitro screening, screening for several Phytophthora species and across several tree species.
One of the main applications of similarity-based virtual screening is to help decide which compounds should be taken forward for in vitro screening.
Aptamers, which are short single-stranded DNA (ssDNA) or RNA, were screened by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX) [16, 17].
We designed an in vitro screening platform by using late passage (passage 5) of WRN -/- MSCs at low confluence.
They relied on a very limited in vitro screen to model a very complex system, and those reviewing the study should be aware of the limitations of the approach and the interpretation of such data.
