Sentence examples for in vitro role from inspiring English sources

In addition, we show that the carboxy terminal domain of the fusion protein FUS-DDIT3 is the part of the protein involved in the represion of the PPARγ2 promoter, which is congruent with the in vitro role of DDIT3 in adipocyte inhibition of 3T3-L1 cells [15] and liposarcoma development in a model using the HT1080 fibrosarcoma cell line [19].

Mice treated with 90Sr could be useful in evaluating the in vitro role of NK cells.

This is based on previously published observations confirming its in vivo and in vitro role as an immunogenic protein.

To ascertain if the in vitro role of PRL-3 correlated with FLT3-ITD-driven AML tumour burden in vivo, we developed a leukaemia mouse model using the lateral tail vein injection of AML cells.

Despite this detrimental in vitro role of P2X7, in SOD1-G93A mice lacking P2X7, the clinical onset of ALS was significantly accelerated and disease progression worsened, thus indicating that the receptor might have some beneficial effects, at least at certain stages of disease.

Given these observations, we investigated in this study the in vivo and in vitro role of the endogenous cardiac glycoside ouabain in regulating the cell growth of malignant neuroblastoma cells through various reported (Schoner and Scheiner-Bobis, 2007) and unreported ouabain-mediated signalling pathways.

Here, we used mammalian cell lines and zebrafish as model systems to address the in vivo and in vitro roles of ATR in activating aromatase expression.

The in vitro roles of PAI-1 in cancer progression were examined and next, we tried to clarify the relationship between LA and PAI-1 effect on angiogenesis in vitro.

Despite numerous reports on the role of P2X7 receptors in ATP-mediated inflammasome activation and mature IL-1 β production in macrophages in vitro, its role in vivo has recently been questioned.

Although immunomodulation by the majority of these agents has been established in vitro, their role in confounding the septic immunophenotype remains unclear.

This work evaluates in vitro the role that the interface of the nanoemulsion has on the physicochemical properties, the stability behavior and the enzymatic degradation after oral intake.