Sentence examples for in vitro profiles from inspiring English sources

Multiple potent GRAs were identified with excellent in vitro profiles and good pharmacokinetics in rat.

Sayes, C. M., Marchione, A. A., Reed, K. L. & Warheit, D. B. Comparative pulmonary toxicity assessments of C-60 water suspensions in rats: Few differences in fullerene toxicity in vivo in contrast to in vitro profiles.

The results obtained indicate that both GIS and ANN model developed were sensitive to input kinetics represented by the in vitro profiles obtained under various experimental conditions.

For two tested formulations there was very good agreement between the GRNN predicted and observed in vitro profiles and estimated coefficients.

This array approach facilitated multi-dimensional SAR around this series and identified functionality responsible for binding affinity, as well as opportunities for modulating the overall in vitro profiles of this class of soluble epoxide hydrolase inhibitors.

The results of the microarray studies show that the in vitro profiles of gene expression cluster per compound and incubation time, and when analyzed in a commercial gene expression database, can predict the toxicity and pathology observed in vivo.

Sehgal, S. N. & Bansbach, C. C. Rapamycin: in vitro profile of a new immunosuppressive macrolide.

The in vitro profile, structure, and first synthesis of this indigoid component is reported.

However, when two optimized representatives (6 and 14) possessing the desired in vitro profile were tested neither reduced the motor activity of mCPP treated animals.

A similar in vitro profile for drug release from NLC containing Precirol ATO 5 was also reported previously [29, 35] (Fig. 4).

Both AT1S and AT2S exhibited a pansomatostatin-like in vitro profile, binding to all five sst1-5 with affinities in the lower nanomolar range.