Sentence examples for in vitro effective from inspiring English sources

Thereafter, the PBK-simulated blood levels at toxic in vivo doses were compared to the respective in vitro effective concentrations.

The model can be used to design and refine in vitro experiments and extrapolate in vitro effective concentrations to in vivo doses that can be applied in risk assessment.

The patients without in vitro effective agents were treated with radiotherapy alone, and were excluded from the initial response evaluation but included in the survival analysis.

In vitro effective rates were calculated for each drug (Table 3 >), and were relatively high in aclarubicin (25%), etoposide (20%), and cisplatin (18%).

However, both studies revealed that compared to other antibiotics, tigecycline and polymyxin B (or its less toxic derivatives, colistin) remained an in vitro effective antimicrobial agent for the treatment of IRABC or XDRABC in Taiwan.

However, the in vitro effective concentration was high because of poor solubility of STB-HO in cell culture study, which should be improved by nanoparticle method, synthesis or new dilution methods in the near future.

Many potent and proven in vitro-effective chemical disinfectants, such as glutaraldehyde, can pose health hazards to staff in direct skin contact or through inhalation, as well as causing unhealthy work environments for staff and patients.

Although methods for gene silencing have been achieved with high efficacy and specificity in vitro, the effective delivery of nucleic acids to specific cells in vivo has been a hurdle for RNA therapeutics.

Thus, the study herein presents a novel comparison where enhancement in vitro contradicted effective inhibition in vivo.

Thus, an IQ of 1 or greater means that the achievable total plasma concentration of the drug is equal to or greater than the in vitro 50% effective concentration, and the higher the IQ translates to a greater predicted efficacy.

If the cultured pathogen was resistant in vitro, but effective in vivo, it was classified as "unknown".