PCC dosing thus was not always respected in view of the French guidelines.
This study aimed to evaluate prospectively PCC use in patients with VKA-related bleeding in view of the French guidelines published in 2008.
The findings are also interesting in view of the recent NICE guidelines for the management of depression in primary and secondary care which promote the use of guided self help, computerized CBT, and exercise in mild depression, but the use of medication and combined treatments in those with treatment resistant or severe depression [ 18].
In view of the Surviving Sepsis Campaign Guidelines and the Tarragona strategy, it makes sense to 'hit hard, early and appropriately'.
In view of the modest effect on guideline use and the considerable resources required for an active, multi-component intervention such as the one in this study, a comparison between different implementation strategies with various components could provide valuable knowledge.
Addressing the role model function of supervisors for residents may be one more way to motivate them to use the guideline, in view of the impact that supervisors have on residents (14 ).
The outcome of the proposed research work should be a European recommendation paper on how to improve the dissemination, integration into the clinical workflow and use at large of clinical imaging guidelines in view of the referral process.
In recent years, imaging guidelines, in view of the referral process, have received much attention from the radiation protection community and international organisations given the increasing number of medical imaging procedures and studies that have shown that about 30% of the imaging procedures performed in Europe were found to be inappropriate (29).
OLT is currently outside the routine remit of UK Transplant Agency guidelines in view of the disease-free survival of <50% at 5 years.
It is however doubtful that managing polypharmacy of elderly patients with multimorbidity can be completely 'covered' by guidelines in view of the heterogeneity of patient characteristics.
In view of the safety of current antidepressants, clinical guidelines have become more and more conservative in determining the maintenance period of ADs [ 18].
