Free-energy calculations demonstrate the stability of the complex and help identify key residues in various interactions based on residue decomposition analysis.
The workgroup is assimilated to a system composed of entities, which are in various interactions managed by a set of coordination and control mechanisms.
They can take part in various interactions of a hydrophobic as well as dipolar and ionic nature depending on the side chain functionalities of the amino acids within the sequence.
We discussed latest findings on how these proteins participate in various interactions to diversify the ANK roles in numerous biological processes, and explored the emerging and evolving field of designer ankyrins and its framework for protein engineering emphasizing on biotechnological applications.
Galectin is extracellularly expressed and involved in various interactions with serum proteins, other cells and extracellular matrix, and variously implicated in cancer-related processes such as metastasis formation and invasiveness.
L2 has also been implicated in various interactions with host factors including cell surface binding [32], [33], actin and dynein binding [34], [35] syntaxin 18 binding [36], and cleavage by the cellular protease furin [37].
For VDAC, which is known to have different functions besides metabolite transport and is involved in various interactions with different proteins, the sequences seems to be more diverged and the identified significantly conserved region comprises β-strands 18 19 (Zeth 2010).
In the past, various interaction fingerprints have been developed and successfully employed for post processing of docking poses.
When students are participating in clinical practice, they enter a highly complex system of workplace learning, in which various interactions affect task performance as well as how and what students learn (Mennin 2010).
