Most infections did not lead to further transmission, although a small number of "super-spreading" events occurred in which single unrecognized cases transmitted to many people, usually in hospitals or households, before appropriate infection control precautions were in place (1 ).
The rarity of CJD, however, in postmortem studies of possibly clinically unrecognized cases of CJD in the elderly has led to the suggestion that the decline in incidence among the elderly is real and unlikely an artifact of a varying sensitivity, by age group, of surveillance [41].
The higher number of Whipple disease cases in white men may be related to a genetic factor or might reflect a large number of unrecognized cases in developing countries.
This suggests that awareness of the less typical manifestations has improved, resulting in the diagnosis of previously unrecognized cases.
We believe the results of this study were unlikely to be affected by any unrecognized cases of extradural spinal tumor in this analysis.
The rise in diagnoses was also generally greater among 14- to 17-year-olds, underscoring the likelihood that these were previously unrecognized cases.
Therefore, there may be many unrecognized cases of LIG4 deficiency.
In total 236 cutaneous side-effects to PPIs have been reported, and we wonder whether some of these could have been unrecognized cases of DI-SCLE.
Nevertheless, CSD often remains unrecognized in cases of cervicofacial lymph node enlargement.
Standard treatment with crosslinking agents such as cisplatinum would be fatal in unrecognized FA patients.
