Sentence examples for in uncoupling of from inspiring English sources

Rotator cuff tears can result in uncoupling of these balanced forces across the joint, resulting in instability.

These findings indicate that a complete loss of betaglycan results in uncoupling of the reciprocal inductive signalling pathways that operate between the metanephric mesenchyme and ureteric epithelium to drive the progression of branching morphogenesis and nephrogenesis.

Therefore, ndi1 expression in ISCs/EBs may result in uncoupling of DILP signaling from nutritional status.

Blocking the IL-1 pathway may result in uncoupling of erosiveness in tophaceous disease.

Down-regulation of CD3ζ expression results in uncoupling of the TCR signal transduction pathways and functional T cell hyporesponsiveness [ 30].

Excessive nutrient processing by mitochondria can result in uncoupling of oxidative phosphorylation and an increased generation of ROS; this, in turn, leads to altered mitochondrial function and further ROS generation.

However patients treated with dopaminergic therapy unexpectedly showed a delayed sleep onset relative to DLMO, suggesting dopaminergic therapy in PD results in an uncoupling of circadian and sleep regulation.

Pharmacological inhibition of DHFR activity by methotrexate, or genetic knockdown of DHFR by RNA interference, diminished intracellular BH4 and increased BH2 levels resulting in enzymatic uncoupling of eNOS in endothelial cells.

MDM2 overexpression in mammary epithelial cells resulted in the uncoupling of S-phase from mitosis, causing multiple rounds of DNA synthesis without cell division.

Some authors suggest that adolescent AN shows a decreased bone turnover overall, in contrast to postmenopausal osteoporosis in which uncoupling of bone turnover is found, i.e. markers of increased bone resorption and decreased bone formation [ 6- 10].

Uncoupling protein 1 (UCP1), which is uniquely expressed in BAT, plays an important role in the uncoupling of oxidative phosphorylation and the conversion of energy into heat to maintain normal body temperature.