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Wrist SPECT/CT is often used as third-line problem solving modality in unclear cases after X-ray and CT or MR imaging.
In unclear cases autopsy has been traditionally employed.
Therefore the use of a three-dimensional imaging might be helpful in unclear cases.
Only data relevant to ATS criteria were collected, and in unclear cases, a radiologist was consulted.
Tumors were considered to have recurred based on their appearance by imaging examination (abdominal ultrasound, CT, or MRI); hepatic arteriography or biopsy was used in unclear cases.
Our data show, that CXCL13 might be helpful in unclear cases and support the presumption that it might be a valuable tool for treatment monitoring.
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In those unclear cases, the full decision rested with the committee.
In clinically unclear cases, a histologic examination is required.
Only in clinically unclear cases lesional detection of VZV-DNA by PCR might be used to confirm the diagnosis.
30– 34 Although in high-grade retroperitoneal cases referral to a sarcoma center is common, referral is sometimes omitted in more unclear cases.
However, the bottom line is that in any unclear case an endoscopic examination should be performed, and a biopsy obtained (Fig. 20).
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