The cost of delivery of IPTi with SP in trial settings to 1000 infants ranged from USD 353 in Ifakara, Tanzania to USD 496 in Navrongo, Ghana.
In trial settings, measurements are performed by trial radiologists in order to assure consistency.
Process evaluations are useful for understanding how interventions are implemented in trial settings.
Sanitation facilities in trial settings were 'improved' in 12 studies, 'unimproved' in 15 studies, and 'unclear' or unreported in 19 studies.
This matter of lack of consistency has already successfully been addressed in trial settings, where measurements are widely performed by trial radiologists.
ISRCTN: ISRCTN93576146 Understanding how interventions are implemented in trial settings is important for interpreting the main trial results and indicating how the intervention might function beyond the trial [ 1, 2].
As outlined (Table 1), exenatide is only approved for subcutaneous administration in the ambulant type 2 patient, but there is experience with its intravenous use in trial settings [ 81, 82].
Randomisation and blinding caregivers, participants, and investigators for treatment allocation are used in trial settings to increase the internal validity and aims to ensure that an effect is solely caused by the intervention[ 6].
Finally, the responsiveness, as measured by ES and RE, of RADAI and RAPID3 compared with other composite clinical indices of CZP therapeutic efficacy suggests that these PROs can be used to assess treatment outcomes in trial settings.
All clinical exclusion criteria were based on conditions that we were not confident of vis-a-vis the effectiveness or safety of TMP-SMX 7 9 and that we opted to exclude considering clinical equipoise in trial settings.
