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The lack of efficacy could have resulted from delay in time to intervention.
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In such a scenario, the time to intervention becomes relevant: early and effective treatment may allow the cell to revert to a normal state, as long as the oxygen machinery (i.e. mithocondria) is intact.
This study goes back in time to actuarial intervention in industrial pensions in the United States.
A secondary outcome (30-min difference in time to operative intervention) mandating inclusion of 420 patients was mentioned in the methods section of the original paper.
Staff physicians devoted a portion of their work time to interventions in the private sector, working in the public sector primarily in cases of emergencies (serious complications) or when performing scheduled caesareans on patients with whom "financial arrangements" (fees paid to the gynaecologist by the patient) were made during their pregnancy care.
Even though a specific pandemic precursor may or may not be identified in time to allow preemptive intervention, prioritizing influenza virus subtypes and antigenic variants for vaccine preparation will be a major step forward.
Therefore, it would have been more appropriate to take more measures extended in time to check the intervention effects.
The recruitment goal was not fully reached due to the need to stop recruitment and begin the intervention in time to allow completion of the intervention before interruption by school vacations.
"Thanks to the fact that an HIV test is routinely recommended to all pregnant women during their antenatal care, most with HIV are diagnosed in time to take up interventions," she says.
41 The sixth issue is that when we analyzed for the presence of disability 35 and cognitive impairment 42, 43 in this study, there was no difference in time to falling between the intervention or control groups.
In addition, a small number of interviews may take place closer in time to receipt of the intervention if this is deemed (a) feasible given recruitment and (b) worthwhile in terms of providing new information to that gleaned from qualitative interviews undertaken in the development phase of the trial.
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