(Well, duh. He's written, directed and starred in two adaptations of the novelist's work).
Results obtained in two adaptation experiments carried out with the bacteriophage MS2 also showed a high number of beneficial mutations in different mutational contexts [ 26, 29].
In two of the three adaptations performed, the RNAP gene was displaced to delay entry and thus delay expression of the RNAP gene.
This has resulted in three main adaptations to IPT for depression.
In the two adaptations to slyD-deficient hosts, however, every change observed was in the lysis gene E (and overlapping gene D, Table 3).
In the four adaptations of Rokyta and Wichman (2009), 12 of 19 changes were in the transgenic capsid or a scaffold protein gene, and at least the first two changes in each adaptation were in those genes.
At high host density, T7 attained a lysis time close to the optimum within 150 generations of adaptation, but the phage failed to approach the optimum at low host density in two separate adaptations of ∼300 generations each.
In one of two adaptations, T7 evolved a compensatory change in a tail gene.
He played Thomas Cranmer in two BBC adaptations, The Six Wives of Henry VIII (1970) and Elizabeth R (1971), before going to on play one of his most well-loved characters, the German Kommandant in Colditz (1972-74).
While he was being compared to Danny Kaye and Jacques Tati, he also played the title roles in two screen adaptations of French classics, Voltaire's Candide (1960), updated to the second world war, and Beaumarchais' The Marriage of Figaro (1961).
