Data from these trials will help to determine the clinical utility of FGFR3 inhibitors for patients with t(4 14) MM and may pave the way for personalized medicine in patients with this incurable disease.
Thus, based on these studies, inactivation of the p53 pathway by the KSHV virus lies in the pathogenesis of this incurable malignancy.
Genetic or chemical modulation of the developmental regulators of exocrine pancreas, such as histone deacetylases (HDACs) and RNA polymerase III (POLR3), may offer new opportunities for improving therapeutic response in this generally incurable disease.
This summer, I had surgery at U.C.L.A. to rewire the nerves in my neck and cure this incurable condition.
This qualitative interview study is part of a larger project that examines chemotherapy use in the incurable phase of cancer.
Mr. Nicklinson himself had once shown athletic prowess as an avid rugby player, but a stroke in 2005 ensnared him in incurable "locked-in syndrome," which he described as a "living nightmare".
Further investigations will now be paramount in order to individualize treatment, to define optimal combination therapies and to integrate molecular characterization for response prediction, in this, as yet, incurable disease.
This flaw, this seemingly incurable default in Rooney's nature, persists.
In response to this often incurable disease course, we have offered allogeneic (related or matched unrelated) allo-HCT to mature T-cell lymphoma patients as salvage therapy, in an attempt to harness a potential graft-versus-lymphoma (GVL) effect.
