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Mutant mitochondrial tRNATrp disturbs the synthesis of mtDNA-encoded respiratory chain complexes subunits; in this case, markedly decreased amounts of mtDNA-encoded CIV subunits predominantly inhibit CIV holoenzyme formation at each assembly process [ 31].
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The legal proceedings in that case markedly changed the conversation about the validity of surrogacy contracts.
Elongating/terminating S2-modified polymerase association, which is usually skewed toward the ends of transcribed regions (6 kb for mRNA, −1 kb for lncRNA in this case), was also markedly lower in KD cells.
These important findings not only confirmed the PGRN-TNFR interaction in human samples, but also indicated that certain modifications, in this case, phosphorylation at Ser81, markedly affected the interactions between PGRN and TNFR (Thurner et al., 2015).
This is in stark contrast to the effect observed in OBF1 deficient IL-7 dependent pro-preB cells: in this case, cellular proliferation is markedly improved in comparison to WT cells [25] and data not shown).
In this case, an extended surgery markedly reduces the quality of life, thus affecting the patient's social life.
We do not know exactly why institutional evaluations of glyphosate differed so markedly in this case because the IARC has yet to publish its full evaluation (that is promised for later in the year).
The image of a bunch of social scientists inflicting pain on laboratory volunteers seems creepily Mengelian, but in this case the experiments involved were markedly less cruel.
In this case, the expression of RasGRP1 markedly increased ELK driven promoter activity.
However, in this case, the calibration sensitivity is markedly lowered which may jeopardize the accuracy of the results.
In this case, the intrahepatic bile ducts were markedly dilated with papillary proliferation in the lumen, and the tumor cells exhibited marked atypical appearance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com