Exact(1)
We hypothesized that individual genes that are differentially regulated after carboplatin exposure (Table 2) might be surrogates for carboplatin-induced changes in their corresponding pathways.
Similar(59)
To analyze the joint effect from multiple SNPs in functional regions that may be associated with Crohn's disease, we first map all the SNPs in the CD dataset into their corresponding pathways and thus implement SCPCA on each pathway to identify those pathways that are statistically significantly associated with the disease outcome.
These genes and their corresponding pathways are summarized in Table 3.
Targeting our subnetworks or their corresponding pathways may result in development of efficient novel drugs for T-ALL treatment.
Since hydrogen and its by-products, acetic and butyric acid, are easier to degrade, promoting their corresponding pathways could result in an improvement of methanogenesis kinetics [ 19].
T helper 1-related genes (Mlecnik et al., 2010) and their corresponding pathways are simultaneously visualized in a CluePedia network (Fig. 1a).
This mutant led to increased production of not only resveratrol but also the flavonoid naringenin, when introduced in their corresponding biosynthetic pathways.
We analyzed the baseline expression levels of the 10 most upregulated genes after carboplatin exposure shown in Table 1, and their 5 corresponding pathways (TNFR2, ATM, NF-kB, NRF2 and cytokine and inflammatory response pathways), in tumors from patients with favorable and unfavorable DFS and OS as identified by the time course signature.
The respective teams did the sensitivity analyses in the corresponding pathways (varying the categorization methods) and adapted their pathway analysis in order to integrate a common structure.
The enzymes identified by Spice are next described in the context of their corresponding metabolic pathways.
Mapping all associations of miRs and genes that appeared in the corresponding pathways, we found significant interactions of prominent miRs (Fig. 3B).
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