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Elimination of self-reactive T cells in the thymus: a timeline for negative selection.
Carpenter, A.C. & Bosselut, R. Decision checkpoints in the thymus.
The control of T cell fate in the thymus.
Most T cells that multiply in the thymus also die there.
While in the thymus, the transplanted cells made insulin and secreted it into the bloodstream.
T cells originate in the bone marrow and mature in the thymus.
They are abundant in the thymus and pancreas.
Xiong, Y. & Bosselut, R. CD4 CD8 differentiation in the thymus: connecting circuits and building memories.
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New naive T cells are only produced in the thymus.
P-gp activity is developmentally regulated in the thymus.
For example, Apc and Bcl11b are downregulated in the thymus.
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