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When ASC specks form in cells transfected with ASC and pyrin, both proteins are always co-localized in the specks (Figure 9A D).
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When PAPA syndrome-causing mutants of PSTPIP1 were transfected with ASC and pyrin (A230T Figure 9T V; E250Q Figure 9W Y), PSTPIP1 appeared in the speck with pyrin over 95% of the time (compared to 70% of the time with wild type PSTPIP1).
While the inspectors had difficulties not only in determination of the specks having a diameter less than 0.2 mm but also in correct diameter measurement for all specks, the CIS had good determination and measurement capability.
The cry is less from the world than from the specks in the universe.
But the specks in the air are not flies.
As they swirl in the roiling disk, the specks occasionally collide and stick together by electromagnetic forces.
Here are a few logs the U.S. should take out of its own eye before telling Iraq and Russia how to handle the specks in theirs.
In the bathroom specks of blood were discovered on the washing machine and a shower curtain.
So far, the scientists have a rough breakdown of the chemical elements in the dust specks, based on X-ray imaging, but they do not know much else.
In Texas 1858, the Speck brothers, Ace and Dicky, drive African slaves on foot.
Overall it seems columnists are obsessed by the speck in a politician's eye, ignoring the log in their own".
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