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Figure 5 contrasts the dSPM estimates derived from EEG and MEG in the same spindle, plotted on the subject's reconstructed cortex, after expansion to reveal sulcal as well as gyral cortex.
However, in these experiments, due to the presence of both intact chromosomes and kinetochore-free chromosome fragments in the same spindle, it was unclear if the chromosome fragments could be "hijacked" by the kinetochore-microtubule generated poleward forces.
Consistent with the low levels of AIR-2, him-8 univalents had 1.7 ± 0.3 times the intensity of REC-8 staining as the inter-homolog region of bivalents in the same spindle.
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Again, in the MEG-dSPM solution, maximal activity is estimated to different cortical lobes and hemispheres in different parts of the same spindle.
Most of nonseparated CEN3 signals stayed in the vicinity of the same spindle pole during time-lapse observation (data not shown); they were therefore mono-oriented on the spindle (Supplemental Results and Discussion, note 1).
In contrast to mitosis, sister chromatids have to be oriented toward the same spindle pole in meiosis-I, while homologous chromosomes are bi-oriented.
Co-orientation of long arms would ensure that sister chromatids are pulled to the same spindle pole in anaphase I following proteolytic cleavage of COH-3/4.
Second, sister chromatids attach to microtubules from the same spindle pole (co-orient) in meiosis I to ensure that spindle forces pull homologs apart but not sister chromatids.
This will result in a metaphase I chromosome mass with both homologs oriented toward the same spindle pole.
Disks are attached on the same spindle, which is rotated by one servo motor.
Strikingly, we found a similar correlation between motor memory and spindle characteristics during the sham night for the same spindle frequencies and electrode locations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com