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For example the rDNA loci in Escherichia coli are arranged in the same orientation as that of replication fork passage.
Remarkably, productive transcription elongation across PERs is usually directional, predominantly in the same orientation as that of the nearest downstream gene.
18 PRAME-like genes and 15 pseudogenes were predicted in the orthologous region of mouse chromosome 4. (These are numbered sequentially Mus_1, Mus_2 etc., in the same orientation as that used for the human and chimpanzee numbering scheme).
Many of the ROCK and GRK inhibitors characterized structurally thus far contact the hinge with the edge of a planar, usually aromatic ring system that binds in the same orientation as that of the adenine ring of ATP.
The random variable O n is binary, with O n =0 indicating that the sequence of read n is in the same orientation as that of its parent isoform, and O n =1 indicating that it is reverse complemented.
The Thr-481 side chain is in the same orientation as that of Ala-481, with the Cγ methyl pointed towards the protein interior and the Oγ alcohol extending into the t1-binding site.
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In addition, Y195 is observed in the same orientation as in the V266H single mutant; that is, it H-bonds directly with T140.
MiMIC insertions in coding introns that are in the same orientation as the transcript (∼50% of coding intron insertions) should function as gene traps (GT).
DAPI and Nissl staining was performed on 100 µm thick fixed brain slices that were cut in the same orientation as the in vivo images were taken.
In two cases it was present in the opposite orientation from that in the parental strain (and in the same orientation as in NCM4139).
The co-crystal structure proves that compound 3 binds in the same orientation as PLP, and confirms the mode of inhibition to be competitive.
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