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We predicted 106 aligned nonidentical residues to be in the same functional class (38 were functionally important).
These null mutations highlight specific functionally significant amino acids, both being in the same functional domain of the Nav1.7 protein.
A wavelet decomposition approach is used to model both fixed-effects and random-effects in the same functional space, meaning that the population-average curve and the subject-specific curves have the same smoothness property.
Sub-networks were generated by selecting genes that were categorized in the same functional GO group.
We show that correlation in branch lengths extends to genes that are involved in the same functional pathway.
For example, YGR032W and YLR342W (glucan synthases) were associated, and they are in the same functional class.
To obtain a more synthetic annotation, the enriched nodes directly connected by a path in the GO graph were grouped together in the same functional cluster.
These results suggest increased γcyto-actin expression does not fortify dystrophin-deficient muscle cell membranes, but γcyto-actin and dystrophin lie in the same functional pathway.
Not all parameters involved in protein localization within the plasma membrane change in the same functional direction over evolution (Figures 2, 3 and 4).
The aim was to evidence co-expression of genes implicated in the same functional network or process or which physically interact.
As in cells, the majority of genes show a modest change (less than 4-fold), are mostly up-regulated, and are mostly enriched in the same functional categories as promoter-bound genes (Figure 8, fourth column).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com