Therefore, setting the threshold to t = 0 will result in the maximal average clustering coefficient and number of edges in the respective functions ACC t) and EN t).
Antigen surface expression density, the respective function in a given cellular background, the level of internalization and, as shown for monocytes, the activation status may govern susceptibility to HM1.24-ETA′ and other immunotoxins.
If a GO category or biological process is significantly overrepresented, which means that a relatively high number of genes assigned to the respective function is present in the selection, this will result in a low P -value.
For SUN and KASH domain proteins written in bold, the respective functions have directly been demonstrated; others have been implicated indirectly nd not defined LINC complexes also act as cytoskeletal organizers (Fig. 1).
In addition to the respective functions of each family member, all XRN proteins redundantly act as endogenous RNA silencing suppressors, probably through eliminating the free 5′ ends of single-stranded RNA templates that can be recognized by RNA-dependent RNA polymerases (Gazzani et al. 2004; Gy et al. 2007).
Worsening of mobility, IADL and BADL disability at 2-year follow was defined as any increase, with respect to baseline, in one or more number of reported difficulties in mobility, IADL, and/or BADL among subjects not already disabled at baseline in all the tasks of the respective functioning domains.
Table 2 shows the conditional probability for each motif Γ i (rows) to implement the function ϕ j (columns).These probability distributions are calculated from the association of a given motif, its possible BRs and the respective functions, as described in [ 26].
The former causes a complete loss of gene function, while the latter refers to a mutation leading to a decreased activity in the respective gene function [ 15].
The annual rate of change in lung function (Δlung function/years) was defined for each participant as lung function at follow-up minus lung function at baseline divided by years of follow-up, such that negative values represent a decline in the respective lung function parameters over time.
Borg and Kaijser [ 10], who opted for estimating individual curves in 20 adults, noted one individual with an exponent >2.8 in the respective power function.
