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These functional RNA molecules are likely to be applicable in the reprogramming of existing gene regulatory systems.
These results suggested the possible involvement of PpCSP1 in stem cell maintenance and in the reprogramming of differentiated chloronema and caulonema cells to chloronema apical stem cells8.
"If we are successful with the use of stem cells or in the reprogramming of cells," she says, "it will mean that people are no longer dying of the things we are dying of today.
"Synthetic biology at its core is about applying engineering best practices to speed up the 'design-build-test' cycles in the reprogramming of existing or construction of new biological systems.
Using the adeno-associated virus-mediated transfer, Wang et al. later demonstrated that the adenovirus transduction-triggered immune response play a critical role in the reprogramming of hepatocytes into β-like cells[56].
Some studies analysed the relationship between drought stress and the expression of the KRP genes involved in the reprogramming of cell proliferation and cell expansion in leaves (Claeys and Inze 2013; Guan et al. 2014).
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This single-cell system will be useful in studying the reprogramming of differentiated cells into stem cells in the absence of potentially confounding effects of surrounding cells.
The method might also prove useful in monitoring the reprogramming of somatic cells into pluripotent descendants and in identification of epigenetic abnormality.
In addition, the reprogramming of biallelic histone modification (BAHM) or ASHM genes in the F1 hybrids exhibited functional diversity.
In addition, the reprogramming of mitochondrial function was proposed as a key adaptation enabling a fetus to survive in a limited environment (rev in [20]).
In terms of the reprogramming of tissue cells into ES cell-like cells (generally referred to as induced pluripotent (iPS) cells), the role of Nanog is still controversial.
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