Sentence examples for in the proportion of integration from inspiring English sources

These results suggest that the 8.0 kb RNP fragment confers a substantial increase in the proportion of integration events that lead to detectable gene expression.

Through their capacity to confer an increase in the proportion of integration events that are productive, together with improvements in the level of transgene expression, RNP CpG island vectors have many other potential applications, including use in mammalian cell-based in vitro screens for drug discovery, transgenic animals for basic research and drug discovery, and gene therapy.

In the LEDGF/p75 knockdowns (Figure 5, orange and yellow shading), the proportion of integration sites in genes was reduced, with the percent change significantly greater in the intensified SupT1 knockdown over many of the gene catalogs studied.

No significant difference was observed between pre-infusion and post-infusion T-cells both in the frequency of integrations within genes (48% vs. 49%) and in the proportion of genes harboring integrations around the TSS (16.3% vs. 14.5%, p>0.1 in all comparisons) (Figure 1B).

Comparison of integration targeting data reported here to earlier data with weaker knockdowns [40] showed that indeed intensifying the LEDGF/p75 depletion further diminished the proportion of lentiviral integration sites in transcription units.

These values were then plotted against the proportion of HIV integration sites in transcription units for that cell type (Figure 9).

In addition to these data on manipulated cell models, we also present additional bioinformatic studies of 15 published HIV integration site data sets in different cell types, which revealed a strong correlation between cell type specific LEDGF/p75 expression levels and the proportion of HIV integration sites in transcription units.

Although GFP-positive cells obtained by the random integration method comprised 59.6%, there was not a great difference in the proportion of GFP-positive cells by the MI-HAC vector or the random integration methods (Table 1).

Significant changes were noted in the proportion of visits related to specific ICD-9 diagnosis codes at NC-VAMC/Lovell FHCC post-integration.

Given the many challenges that IMGs experience in workforce integration in Canada, it is reassuring that no significant difference exists in the proportion of Canadian and IMG graduates who experienced IHD in our setting.

China also still maintains a steady increase in the proportion of ad spending in the world.