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This orientation is comparable to that observed in Polβ and Polλ complexed with gapped DNA substrates, prompting us to investigate if these residues play more specific roles in the precise alignment of the two ends after productive synapsis.
A growing body of evidence suggests that, for some enzymes, there is an interplay between catalysis and protein conformational flexibility, with the involvement of dynamical processes and atomic motions in the precise alignment of the substrate with the enzyme (as reviewed by Benkovic).
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The advantages of in vitro measurements include the precise alignment of the tissue to be examined within the test configuration and the potential to carry out measurements over longer periods.
It is this, the precise alignment of Earth and Mars in 2018 and the tiny size of the vehicle, her crew and the systems of life support required to maintain them, that brings the 501-day mission into the theoretical throwing capabilities of today's rocket launchers and the boundary of possibility.
Even though this diffraction pattern has been acquired from both triangles, we can observe only one set of diffraction spots with 6-fold symmetry, showing the precise alignment of lattices in both of the islands.
The adherends were cured in a jig (Fig. 3) that ensures the precise alignment of the adherends and correct overlap length.
The ability of collagen to provide a strong network and to fully mineralise depends on the precise alignment of the type I collagen molecules in the collagen fibre.
He said: "The scale of that risk will depend on the precise alignment of the route.
However, the decoding is highly dependent on the precise alignment of transparencies by hand.
They are followed by the plumber-uppers, who use cables and levels to ensure the plumbness, the precise alignment, of the beams and columns.
The central pattern exhibits the precise alignment of notches.
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