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Contemporary trends in the pharmaceutical development emphasize the utility of advanced computer tools to facilitate formulation of new medicines.
A current challenge in the pharmaceutical development of this drug is to improve its solubility without compromising stability and other valuable properties.
The current regulatory environment based on the ICH guidelines encourages a systematic and science-based approach in the pharmaceutical development, required by the "Quality by design" concept.
On-line compound isolation (using column switching) for the analysis of complex mixtures encountered in the pharmaceutical development process has been investigated.
Examples of different mathematical modeling techniques (mechanistic, empirical and hybrid) in the pharmaceutical development and process monitoring or control are provided in the presented review.
In the present commentary, the role of cocrystals in the modulation of material properties and challenges involved in the pharmaceutical development of cocrystals have been discussed.
Similar(46)
Although the biggest successes have been in technology, including the pharmaceutical development company Alizyme and Robotic Technology, it also took good gains in the likes of Ramco Energy and optronics manufacturer Gooch & Housego.
Addressing safety concerns such as drug-induced kidney injury (DIKI) early in the drug pharmaceutical development process ensures both patient safety and efficient clinical development.
Initial clinical evaluation of new therapies in cancers that are prevalent in the Western population is the standard in pharmaceutical development and delays demonstration of their possible use in the Asian population.
The earliest indicator used to assess torsadogenic risk in the pharmaceutical compound development process is usually based on the hERG IC50 value; compounds that block hERG too readily are discarded.
One of the major challenges in pharmaceutical development is the poor dissolution performance of drugs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com