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Exact(2)
Significant differences were seen in the pattern of relapse.
Furthermore, no difference in the pattern of relapse was found and also the number of nodal relapses was the same between the two groups (Table 5).
Similar(58)
There were no clear differences in the pattern of relapses and, specifically, there was a similar number of retroperitoneal relapses between the two arms.
There are only 10 studies in the literature which fully present the pattern of relapse after breast cancer with regards to how that relapse is detected.
Surprisingly, the pattern of relapse in JACLS cohort, 9 of 82 patients, was unique: eight of nine patients relapsed during the maintenance phase and one patient had primary induction failure.
The pattern of relapse in patients with locally advanced rectal cancer and the tolerability of treatment [ 37, 38] (Mawdsley et al, 2005; Rasheed et al, 2006) call into question the approach to preoperative intensification of chemoradiotherapy currently under investigation elsewhere.
However, the pattern of relapse was unique in the present study, especially in JACLS cohort: eight of nine patients relapsed during the maintenance phase and one patient had primary induction failure, suggesting that leukemic blasts in these patients initially showed resistance to the chemotherapeutic agents used.
The pattern of relapse detection in this cohort is very different from that reported in any of the cohorts we have analysed here.
The pattern of relapse included distant metastases in more than 95% of our patients, similar to earlier reports (Argani et al, 2000).
Also, the pattern of relapse (local vs distant metastases) was studied in relation to the expression of the three markers.
It is also likely that new hormonal therapies will alter the pattern of relapse so that even fewer relapses occur in the first 3 years after treatment (The ATAC Trialists Groupp, 2005).
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