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Critics have suggested that there were errors in the original experiments and that resveratrol did not in fact activate sirtuins directly.
In the original experiments, a posterior malleolar fracture or posterior talofibular ligament rupture was named stage three.
Both aged and young animals were included in the original experiments but the tumor incidence in animals younger than 25 months was very low.
Using only the luminance Y (ITU-R BT.601), as in the original experiments of SUSAN [21], is not appropriate because there are many edge samples that do not appear on the luminance channel, but only on the chrominance channels.
This breeds what researchers call "learned helplessness" -- a dangerously slippery slope: in the original experiments on dogs, whose motivational neural systems are like our own in important ways, it was very easy to train them in helplessness but very, very hard to teach them later that they could actually walk a few steps to escape from painful electric shock.
Some giggled at the Learner's protests, as was observed by Milgram in the original experiments.
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An important point in considering the original experiments by Adey and colleagues is the distinction between the ELF amplitude-modulated RF signals used in their studies and the pulsed GSM RF fields produced by modern mobile phones.
The quantitative data from these genome manipulation studies are not only useful in interpreting the original experiments but also valuable to researchers employing similar approaches.
Such a control antibody was used in some of the original experiments in vitro, (PNAS, Figure 3A-C), but apparently the antibody later became "unavailable" and hence was not included in subsequent in vitro or any animal experiments.
That is less than in the original experiment, but not enough to be significant.
Mischel and his colleagues tracked some of the children as they grew up, and then claimed that those who managed to hold out for longer in the original experiment performed better at school, and went on to become more successful in life, than those who couldn't resist the temptation to eat the treat before the researcher returned to the room.
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