Here a new concept, based on the thermodynamic extremal principle, is introduced, which allows a detailed study of the transient processes in the migrating interface starting from a given initial configuration.
Furthermore, as S1p2 functions in the endoderm rather than in the migrating heart progenitors, we tested for endodermal expression of Grk2/3 and β-arrestin.
In the "migrating endothelial type", migratory cells positive for both hVm and CD31 were dominant in the interspaces of the murine kidney parenchyma (Figure S1A).
Several Ephs and ephrins have been shown to be induced by hypoxia (Vihanto et al., 2005) and we know that wounds are hypoxic (Chang et al., 1983); it is known that wnt signaling can regulate ephrin-Bs (Batlle et al., 2002), and there is good evidence that wnt signaling pathways are activated in the migrating wound epidermis (Okuse et al., 2005).
Our previous studies showed that a large number of genes expressed specifically in the migrating primordium have common roles in collective cell migration and cancer progression (Gallardo et al., 2010).
For example, keratinocytes in the migrating front deposit laminin 5, which serves as a track to allow subsequent keratinocytes to migrate on [55].
For example, keratinocytes in the migrating front deposit laminin 5, which serves as a track to allow subsequent keratinocytes to migrate [52].
FOXD3 is expressed in the migrating neural crest cells that give rise to glia and neurons, but is not seen in the later migrating, melanocyte-fated crest cells.
A role for caveolae in cell migration has also been described [23], so localization of caveolae in the migrating RMEC was identified by immunocytochemistry for caveolin-1.
These structural changes occurred due to the dissolution of sucrose particles in the migrating moisture and due to the swelling of cocoa powder in the presence of moisture.
Expression of many MMPs-encoding genes was shown by microarray and qPCR analyses to increase in the migrating epithelium of wounded corneas.
